Predicted Lineups
Liverpool possible starting lineup:
Kelleher; Bradley, Gomez, Quansah, Tsimikas; Clark, Mac Allister, McConnell; Elliott, Danns, Gakpo
Southampton possible starting lineup:
Lumley; Bree, Stephens, Bednarek, Walker-Peters; Rothwell, Smallbone, Aribo; Edozie, Adams, Sulemana
Winning the first domestic honour of the season certainly came at a significant cost for Liverpool, who saw Ryan Gravenberch leave the Wembley field on a stretcher owing to an awful challenge from Moises Caicedo, and Wataru Endo was also seen departing on crutches after the game.
All of Mohamed Salah, Dominik Szoboszlai and Darwin Nunez - who was filmed running amok during the celebrations - also failed late fitness tests and were not part of the matchday contingent on Sunday, leaving Klopp to concede that he may struggle to field a full XI for the midweek tie after their gruelling Wembley effort.
Stefan Bajcetic (calf), Thiago Alcantara (muscle), Ben Doak (knee), Joel Matip (knee), Trent Alexander-Arnold (knee), Diogo Jota (knee), Alisson Becker (hamstring) and Curtis Jones (shin) make up the Reds' definite absentees, and only the latter might be back in action before next month's international break.
Speaking of players leaving on crutches, Southampton's on-loan Newcastle winger Ryan Fraser required such aids after sustaining a knee problem in the first half of his side's loss to Millwall, and Martin has already ruled the Scotsman out of the fifth-round affair.
Fraser joins Ross Stewart (muscle) and Juan Larios (unspecified) in the St Mary's infirmary, and the visiting manager cannot call upon David Brooks to deputise for his teammate; the Bournemouth loanee is cup-tied on account of representing the Cherries earlier in the tournament.
Samuel Edozie and Kamaldeen Sulemana should therefore be drafted back into the attacking line out wide, but unlike Brooks, fellow Bournemouth-owned man Joe Rothwell is eligible to play and could be a contender to freshen up the midfield pack in the possible absence of Flynn Downes.